In Genesis 1, creation and the ordering of what is created take place when God speaks the divine command, and the idea of the creative word of God is important in the New Testament. John 1: 1-14 presents Jesus as the word of God incarnate. The Spirit of God (the power of God) is referred to in Genesis 1:2 and it can be held that the doctrine of the Trinity is foreshadowed in Genesis 1. Some commentators attach significance to the Hebrew word, elohim, a plural form, which is used for God in Genesis 1 and which can help clarify the understanding of the pronoun 'we' in Genesis 1: 26. 'We' can be taken to mean God in his nature of the Trinity.

Paul sees a connection between the first man, Adam, who sinned, and Jesus Christ the 'new man' who destroyed sin (Romans 5: 12-19), setting mankind free from the curse of Adam, and Luke 3: 38 implies the same. Paul refers to the one ancestor of all mankind when Paul preaches in Athens (Acts 17: 26). Jesus teaches about the right kind of marriage relationship for man and woman with reference to the Genesis story (Matthew 19:4-9 and Mark 10:2-12). The final transformation of the world when God's purpose in making it has been fulfilled is referred to in several passages such as 2 Peter 3:10-13, Mark 13:24-27. This transformation will be the prelude to the final revelation of God's glory to the human race. Space, time and matter as we now know them had their beginning in God's plan, and will have an ending. The book of Revelation is much concerned with this: 'Then I saw a new heaven and a new earth. The first heaven and the first earth disappeared, and the sea vanished.... "Now God's home is with mankind. He will live with them, and they shall be his people.... There will be no more death, no more grief or crying or pain. The old things have disappeared'" (Revelation 21: 1-4).